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October 16, 2025

Pharmaceutical companies prepare for the economic crisis is an impact and an opportunity

The first major event was the subprime mortgage crisis in the United States, which eventually led to the financial collapse triggered by the bankruptcy of Lehman Brothers. This then escalated into a global financial crisis, further deepening into a worldwide economic downturn. In fact, the signs of this economic crisis had already appeared last year at this time—rising oil prices, driven by increased energy costs from alternative sources, and soaring raw material prices. Many of these so-called "upward trends" were artificial and did not align with the natural laws of economic development. As a result, adverse economic impacts served as the prelude to the larger crisis. Pharmaceutical companies responded to the crisis in various ways. According to statistics, there are no more than three main strategies they adopted. First, many companies opted for layoffs. A prime example is Merck, which announced the layoff of 7,200 employees around the same time it released its third-quarter financial report—equivalent to 12% of its total workforce. Similarly, Wyeth also implemented cost-cutting measures through staff reductions, planning to cut up to 10% of its 50,000 employees by 2011. Second, pharmaceutical giants focused on building up cash reserves. As the saying goes, “If you have money in your hands, you won’t be anxious in your heart.” This approach has been widely adopted by major U.S. pharmaceutical companies. According to data from Capital IQ, large pharmaceutical firms currently hold substantial amounts of cash and short-term investments. Pfizer, for instance, reported a cash flow of $26.2 billion and a strong operating cash flow of $14.8 billion. While other companies may not be as financially robust, their positions are still significantly better than those in other industries facing funding shortages. Eli Lilly, for example, holds only $5.2 billion in cash and has a cash flow of $5.4 billion, though it recently spent $6.5 billion to acquire Ingram Micro Biotech. Third, companies turned to mergers and acquisitions as a strategy for growth. By acquiring smaller biotech firms, they aimed to strengthen their technological capabilities and expand their pipeline of new drugs. During the crisis, small and medium-sized biotech companies saw their stock prices drop significantly, making them attractive targets. These companies, often struggling with negative cash flows and limited access to financing, were forced to sell off key assets or even entire divisions to larger pharmaceutical firms. The formation of the economic crisis can be traced back to a combination of factors. Long Yongtu once stated on CCTV that the crisis was largely self-inflicted by the U.S., due to excessive consumption and weak financial regulation. He emphasized that the American model of spending ahead of time and relying heavily on credit cards needs to change. Similarly, Lin Yifu, former chief economist of the World Bank, pointed out that the crisis was rooted in long-term structural issues such as relaxed financial regulations and rapid financial innovation. The bursting of the dot-com bubble led to an aggressive monetary policy that fueled the housing market, ultimately creating the conditions for the crash. The impact of the crisis was widespread. Initially, the financial sector suffered the most, with stock markets plummeting and wealth eroding rapidly. As the crisis spread to manufacturing, people found their savings shrinking and the value of money declining. This led to reduced consumer spending, including in the healthcare sector. For the first time in a decade, Americans began cutting back on medical expenses, with some patients with chronic conditions reducing or stopping their medication altogether. Experts warn that this could lead to higher overall healthcare costs in the long run, as untreated conditions may worsen over time. This trend is not unique to the U.S. Other countries, even those with strong public healthcare systems, are also facing budget constraints. Governments may struggle to maintain current levels of support for medical care, especially as the crisis continues. Despite the challenges, the crisis also created opportunities. First, it accelerated industry reshuffling. Companies that had become inefficient or overstaffed were forced to streamline operations, giving more agile and innovative firms a chance to thrive. Second, for small and medium-sized enterprises, being acquired by larger corporations provided stability and a path forward. Third, the crisis pushed technological advancements forward, accelerating the commercialization of new drugs and treatments. This not only benefited patients but also opened up new markets for companies. As Mencius once said, “Born in hardship, die in comfort.” When we understand the true nature of the crisis, its dangers are not as severe as they seem. Instead, it reveals hidden opportunities that can help us rebuild with renewed confidence and resilience.

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