October 16, 2025
Pharmaceutical companies prepare for the economic crisis is an impact and an opportunity
The first major event was the subprime mortgage crisis in the United States, which eventually triggered the financial crisis following the collapse of Lehman Brothers. This quickly escalated into a global financial meltdown and later evolved into a full-blown economic crisis. In fact, signs of this economic downturn had already appeared last year at this time, with soaring oil prices driven by rising energy costs and increased demand for alternative energy sources. Alongside that, the prices of various raw materials also surged. Many of these "booms" were artificial, fueled by speculative behavior rather than real economic fundamentals. As a result, negative economic impacts served as the early warning signs of the coming crisis.
Pharmaceutical companies responded to the crisis in several ways. According to industry reports, there are generally three main strategies adopted by multinational drug firms.
First, many companies turned to layoffs. For example, Merck announced the reduction of 7,200 employees alongside its third-quarter earnings report—equivalent to 12% of its workforce. Similarly, Wyeth planned to cut up to 10% of its 50,000 employees by 2011 in an effort to reduce costs. These moves reflect the pressure on pharmaceutical firms to streamline operations during uncertain times.
Second, companies focused on building up their cash reserves. The saying "hands have money, heart stays calm" applies well to many large pharmaceutical firms. According to data from Capital IQ, top U.S. pharmaceutical companies hold significant amounts of cash and short-term investments. Pfizer, for instance, reported a cash flow of $26.2 billion and $14.8 billion in operating cash flow. While other companies like Eli Lilly may not have as strong liquidity, they still fare better compared to many other industries facing funding shortages.
Third, many companies took advantage of the crisis through mergers and acquisitions. By acquiring smaller biotech firms, they could strengthen their R&D pipelines, expand their product portfolios, and gain access to new technologies. During the crisis, small and medium-sized enterprises (SMEs) faced difficult choices due to low stock prices and limited access to capital, often forcing them to sell key assets or even entire businesses to larger players.
The economic crisis itself stemmed from a combination of factors. Long Yongtu, former Chinese trade negotiator, pointed out that the crisis was largely self-inflicted by the U.S., driven by excessive consumption, lax financial regulation, and overreliance on credit. Experts like Lin Yifu also highlighted structural issues, such as the dominance of the market economy, relaxed financial regulations, and the aftermath of the dot-com bubble. These factors contributed to a housing bubble and eventual economic collapse.
The impact of the crisis was widespread. Financial markets suffered first, with stock values plummeting and wealth eroding rapidly. As the crisis spread to the manufacturing sector, people saw their purchasing power shrink, leading to reduced consumer spending. This had a direct effect on the healthcare sector, where many Americans began cutting back on medical expenses for the first time in a decade. Patients with chronic conditions sometimes stopped taking medications, raising concerns about long-term health outcomes.
Experts warned that reducing medication could lead to more severe health problems down the line, ultimately increasing overall healthcare costs. Even Bill Gates expressed concern about declining U.S. healthcare spending. Similar situations were likely to occur globally, especially in countries where governments struggled to maintain public healthcare funding amid the crisis.
Despite the challenges, the crisis also brought opportunities. First, it accelerated industry reshuffling, allowing larger companies to restructure and become more efficient. Second, SMEs that were acquired or partnered with bigger firms could survive and continue their operations. Third, the crisis pushed technological innovation forward, enabling faster development and commercialization of new drugs and treatments.
As Mencius once said, “Born in hardship, die in comfort.†When we understand the true nature of the crisis, its dangers are less daunting. It presents an opportunity for growth, transformation, and renewed confidence in the future.
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